Joo Kheng Goh
Monash University Malaysia, Malaysia
Title: Anti-inflammatory and wound healing activities of Hemisgraphis alternata
Biography
Biography: Joo Kheng Goh
Abstract
Therapeutic properties of plant are attributed to bioactive compounds found within them. These compounds can be promising candidates for drug development. This presentation focused on the wound healing and anti-inflammatory properties of Hemigraphis alternata and that the isolation and identification using chromatography and spectroscopic methods is currently employed. Available treatments for wound healing and inflammation are antibiotics and anti-inflammatory drugs, which some are reported to be high cost, low availability and associated with adverse effects. Therefore there is a need to search for alternatives treatments and plant-based drugs represent a key prospect to it. The leaves of Hemigraphis alternate exhibited promising wound healing and anti-inflammatory activities through scratch assay, tube formation assay, nitric oxide production inhibition assay, cytokine TNF-α production inhibition assay and lipoxygenase enzyme inhibition assay. To the best of our knowledge, this is the first report on the bioactivities of Hemigraphis alternata.
