Medicinal Chemistry for Drug Discovery
Medicinal chemists are critical to the success of a drug development effort, relying on their knowledge and skill in current organic chemistry, disease biology, in vitro and in vivo pharmacological screening, and pharmacokinetic features to maximize efficacy while decreasing size. The process of selecting and synthesizing compounds that establish structure–activity correlations and achieve efficacy and safety in preclinical animal testing is aided by medicinal chemistry.
- Pharmacological Screening
- Pharmacokinetics
- Structure activity
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