Pharmacokinetics and Pharmacodynamics
Pharmacokinetic is the quantitative analysis of drug movement in, through and out of the body. Intensity of effect is related to concertation of the drug at the site of action, which depends on its pharmacokinetic properties. Pharmacokinetics also includes the study of the time course of drug absorption, distribution, metabolism, and excretion.
Pharmacodynamics is the study of physiological and biological effect of drugs and also correlation between drug concentration at the site of action and the resulting effect, including the time course and potency of therapeutic and adverse effects. The effect of a drug present at the site of achievement is determined by that drug’s binding with a receptor. Receptors may be present on neurons in the central nervous system to depress pain sensation, on cardiac muscle to affect the intensity of contraction, or even within bacteria to disrupt maintenance of the bacterial cell wall.