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Brian W Dymock


Brian W Dymock

University of Singapore, Singapore

Biography

Brian W Dymock is currently an Associate Professor at NUS and Deputy Director of the NUS Drug Development Unit (DDU). Following a PhD in organic synthesis in the UK, Brian worked as a medicinal chemist in the pharma and biotech industry for over 20 years. In Singapore, he was the Head of Chemistry at S*BIO contributing to the discovery of Pacritinib and Pracinostat. In 2012, he joined NUS Pharmacy. He has a special interest in designed multiple ligands and fragment screening and has established the first fragment screening platform in NUS. He has published over 80 papers and patents.

Abstract

Abstract : Designed bispecific molecules selectively inhibiting both jak2 and hdac at low nanomolar concentrations