Mohammed Moayyad Shukr
University of Salahaddin, Iraq
Title: Determination of some heavy metals in blood serum of pregnant women who induced miscarriage using ICP technique
Biography
Biography: Mohammed Moayyad Shukr
Abstract
Introduction: Inductively coupled plasma - optical emission spectrometry (ICP – OES) is a powerful tool for the determination of metals in a variety of different sample matrices (1). Abortion is defined as the termination of a pregnancy resulting in or closely followed by the death of the embryo or fetus (2). It also called miscarriage which is the loss of the pregnancy prior to viability (before 22 weeks of pregnancy or less than 500 g) (3). Aim: The aim of this study was to determine the concentration levels of (arsenic, calcium and manganese) in blood serum of women who induced miscarriage in their first trimester (first 14 weeks of gestation) and healthy pregnant women with no history of miscarriage as control. Material and methods: Serum concentrations of heavy metals like (arsenic, calcium and manganese) were assayed using (ICP – OES) technique in (n = 50) patients (women who induced miscarriage) and (n = 15) healthy pregnant women (control). Results: Results were expressed as (Mean ± S.E.M.), the results showed that mean serum concentration levels of arsenic, calcium and manganese in patients were (0.0569 ± 0.0002), (5.547 ± 0.1033) and (0.0762 ± 0.00023) mg L-1 respectively, while in controls were (0.0371 ± 0.0009), (8.415 ± 0.1215) and (0.0783 ± 0.00025) mg L-1 respectively. Differences in serum arsenic, calcium and manganese between patients and controls were highly significant, (P value < 0.0001). Conclusion: The study showed that there was a highly significant reduction in serum levels of calcium and manganese in patients as compared to control group, while there was a highly significant increase in serum levels of arsenic in patients as compared to control group.