Aiichiro Nagaki
Kyoto University, Japan
Title: Synthesis of Organofluorine Compounds Using Flow Microreactors
Biography
Biography: Aiichiro Nagaki
Abstract
Organo-fluorine compounds are the substances of considerable interest in various industrial fields due to their unique physical and chemical properties. Despite increased demand in wide fields of science, synthesis of organofluorine compounds is still often faced with problems. Recently, flow microreactor synthesis has emerged as a new methodology for producing chemical substances with high efficiency. Here we report a flow microreactor method for the synthesis of organofluorine compounds based on the generation of unstable fluoro- substituted organolithiums involving perfluoroalkyllithiums and subsequent reactions that are not compatible with the generation process.