Zaraniah binti abdullah
University of Malaya, Malaysia
Title: BIOLOGICAL ACTIVE 1, 2, 4-TRIAZOLE DERIVATIVES.: SYNTHESIS AND BIOLOGICAL STUDIES
Biography
Biography: Zaraniah binti abdullah
Abstract
Ethyl 2-(ethylsulfanyl)benzoate was prepared by treating bromoethane with potassium carbonate and thiosalicyclic acid. Ethyl 2-(ethylsuffanyl)benzoate was then converted to ethyl 2-(ethylsulfanyl)benzohydrazide. A series of 1-acythiosemicarbazides were then prepared from to ethyl 2-(ethylsulfanyl)benzohydrazide , followed by cyclisation to form 1, 2, 4-triazole derivatives. The structures of intermediates and desired compounds were confirmed by spectroscopic analysis. In vitro DPPH radical ccavenging activities of 1, 2, 4-triazole derivatives were studied and will be reported.