Heterocyclic Chemistry
New advances in synthetic methodologies that allow rapid access to a wide variety of functionalized heterocyclic compounds are of critical importance to the medicinal chemist as it provides the ability to expand the available drug-like chemical space and drive more efficient delivery of drug discovery programs. Furthermore, the development of robust synthetic routes that can readily generate bulk quantities of a desired compound help to accelerate the drug development process. While established synthetic methodologies are commonly utilized during the course of a drug discovery program, the development of innovative heterocyclic syntheses that allow for different bond forming strategies are having a significant impact in the pharmaceutical industry. This review will focus on recent applications of new methodologies in C-H activation, photoredox chemistry, borrowing hydrogen catalysis, multicomponent reactions, regio- and stereoselective syntheses, as well as other new, innovative general syntheses for the formation and functionalization of heterocycles that have helped drive project delivery.
- Five-membered heterocycles with one heteroatom
- Five-membered heterocycles with two and more than two heteroatoms
- Benzo-fused five-membered heterocycles with one heteroatom
- Meso-ionic heterocycles
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- Psychiatric Comorbidities in Neurological Disorders - Neurology Congress 2025 (UK)
- Psychiatric Disorders - Neuroscience 2025 (France)
- Psychiatric neuroscience - Neuroscience Congress-2025 (France)
- Psychiatry - Mental Health Congress 2025 (France)
- Psychiatry and Psychology - Neurogenetics 2025 (Canada)
- Psychiatry Mental Health Disorders - Dementia-2025 (Switzerland)
- Psychological Research - Mental Health Congress 2025 (France)
- Psychotherapy and Counselling - Mental Health Congress 2025 (France)
- Public Health Initiatives and Advocacy - Alzheimers-2025 (France)
- Rapid Sleep Diagnostics - SLEEP DISORDER 2025 (Netherlands)
- Rare Neurological Disorders and Case Studies - Neurological Disorders 2025 (Netherlands)
- Recent Studies & Case Reports - Dementia-2025 (Switzerland)
- Regenerative Medicine and Stem Cell Therapy for Spinal Disorders - Spine 2025 (Italy)
- Rehabilitation and Neuroplasticity - NEUROSCIENCE_2025 (France)
- Rehabilitation and Restorative Therapy in Stroke - Stroke Summit 2025 (Canada)
- Risk factor and Prevention of Stroke - Stroke Summit 2025 (Canada)
- Risk factors, Diagnosis, Medications, and Recovery - Stroke Meeting 2025 (France)
- Robotic Neurosurgery - Neuroscience Congress 2025 (Canada)
- Robotic Neurosurgery - CNS 2025 (Germany)
- Role of Inflammation and Oxidative Stress in Vascular Dementia - Vascular Dementia Congress 2025 (Switzerland)
- Schizophrenia - Neuroscience Congress-2025 (France)
- Screen Time Effects - SLEEP DISORDER 2025 (Netherlands)
- Shift Worker Sleep Tips - SLEEP DISORDER 2025 (Netherlands)
- Skull Base Surgery: Techniques and Outcomes - Neuro Surgery 2025 (UK)
- Sleep Apnea Device Overview - SLEEP DISORDER 2025 (Netherlands)
- Sleep disorder - Mental Health Congress 2025 (France)
- Sleep Disorders - BRAIN DISORDER - 2025 (France)
- Sleep Disorders and Circadian Neuroscience - NEUROSCIENCE_2025 (France)
- Sleep Disorders and Their Neurological Implications - Neurology Congress 2025 (UK)
- Sleep Disorders: Pathophysiology and Management - Neurological Disorders 2025 (Netherlands)
- Sleep Hygiene Essentials - SLEEP DISORDER 2025 (Netherlands)
- Sleep in Mental Health - SLEEP DISORDER 2025 (Netherlands)
- Sleep Myths vs. Facts - SLEEP DISORDER 2025 (Netherlands)
- Spinal Biomechanics and Kinesiology - Spine 2025 (Italy)
- Spinal Cord Injuries: Innovations and Rehabilitation - Neurological Disorders 2025 (Netherlands)
- Spinal Cord Injuries: Surgical Management and Rehabilitation - Neuro Surgery 2025 (UK)
- Spinal Cord Injury: Advances in Treatment and Regeneration - Neurology Congress 2025 (UK)
- Spinal Deformities: Diagnosis and Treatment Innovations - Spine 2025 (Italy)
- Spinal Disorders and Spine Surgery - CNS 2025 (Germany)
- Spinal Tumors: Diagnosis, Treatment, and Outcomes - Spine 2025 (Italy)
- Spine and Spinal disorders - Neuroscience Congress 2025 (Canada)
- Spine Disorders in the Aging Population: Challenges and Solutions - Spine 2025 (Italy)
- Sports-Related Spinal Injuries: Diagnosis, Prevention, and Treatment - Spine 2025 (Italy)
- Sports-Related Spine Injuries and Rehabilitation - Spine 2025 (Italy)
- Stem Cell Therapy and Regenerative Medicine in Neurosurgery - Neuro Surgery 2025 (UK)
- Stem Cells & Brain Repair - Neuroscience 2025 (France)
- Stigma and Mental Health - EURO MENTAL DISORDER 2025 (France)
- Stress and Sleep Connection - SLEEP DISORDER 2025 (Netherlands)
- Stroke - Stroke Summit 2025 (Canada)
- Stroke & Neurological Disorders - Neuroscience 2025 (France)
- Stroke and Cerebrovascular Diseases - Stroke Meeting 2025 (France)
- Stroke and Cerebrovascular Disorders - BRAIN DISORDER - 2025 (France)
- Stroke and Cerebrovascular Disorders - NEUROSCIENCE_2025 (France)
- Stroke and Neurological Disorders - Neuroscience Congress 2025 (Canada)
- Stroke and Post-Stroke Dementia: Prevention and Management - Vascular Dementia Congress 2025 (Switzerland)
- Stroke and recovery - Neuroscience Congress-2025 (France)
- Stroke Management and Cerebrovascular Disorders - Neurological Disorders 2025 (Netherlands)
- Stroke Rehabilitation and Brain Hemorrhage - Stroke Meeting 2025 (France)
- Stroke risk, phenotypes, and death in COVID-19 - Stroke Meeting 2025 (France)
- Substance Abuse and Mental Health - EURO MENTAL DISORDER 2025 (France)
- Suicide Prevention Strategies - EURO MENTAL DISORDER 2025 (France)
- Targeting Neurovascular Dysfunction in Neurodegenerative Diseases - Vascular Dementia Congress 2025 (Switzerland)
- Tauopathies and Synucleinopathies: Molecular Mechanisms of Neurodegeneration - Vascular Dementia Congress 2025 (Switzerland)
- Technological Innovations in Mental Health - EURO MENTAL DISORDER 2025 (France)
- The Future of Neurodegenerative Disease Therapy: Stem Cells and Regenerative Medicine - Vascular Dementia Congress 2025 (Switzerland)
- The Future of Spinal Robotics and Smart Wearable Technologies - Spine 2025 (Italy)
- The Impact of Epilepsy on Cognitive Function and Quality of Life - Epilepsy 2025 (Spain)
- The Impact of Epilepsy on Cognitive Function and Quality of Life - Epilepsy 2025 (Spain)
- The Impact of Space Travel and Microgravity on the Spine - Spine 2025 (Italy)
- The Intersection of Mental Health and Chronic Spine Disorders - Spine 2025 (Italy)
- The Role of Neurostimulation in Epilepsy Management - Epilepsy 2025 (Spain)
- The Role of Neurostimulation in Epilepsy Management - Epilepsy 2025 (Spain)
- The Role of Nutrition and Lifestyle in Spinal Health - Spine 2025 (Italy)
- The Role of Seizure Monitoring and Technology in Epilepsy Management - Epilepsy 2025 (Spain)
- Traumatic brain injury - Neuroscience Congress-2025 (France)
- Traumatic Brain Injury - Brain Disorders-2025 (USA)
- Traumatic Brain Injury (TBI) and Neurotrauma - Neuro Surgery 2025 (UK)
- Vascular Dementia - Euro Dementia 2025 (Germany)
- Women's Mental Health - EURO MENTAL DISORDER 2025 (France)
- Women’s Sleep Health - SLEEP DISORDER 2025 (Netherlands)
- Workplace Mental Health - EURO MENTAL DISORDER 2025 (France)